A systematic review of dose-volume predictors and constraints for late bowel toxicity following pelvic radiotherapy
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چکیده
منابع مشابه
Systematic Review of the Relationship between Acute and Late Gastrointestinal Toxicity after Radiotherapy for Prostate Cancer
A small but meaningful percentage of men who are treated with external beam radiation therapy for prostate cancer will develop late gastrointestinal toxicity. While numerous strategies to prevent gastrointestinal injury have been studied, clinical trials concentrating on late toxicity have been difficult to carry out. Identification of subjects at high risk for late gastrointestinal injury coul...
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BACKGROUND In early-phase studies with targeted therapeutics and radiotherapy, it may be difficult to decide whether an adverse event should be considered a dose-limiting toxicity (DLT) of the investigational systemic agent, as acute normal tissue toxicity is frequently encountered with radiation alone. We have reanalyzed the toxicity data from a recently conducted phase 1 study on vorinostat, ...
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ژورنال
عنوان ژورنال: Radiation Oncology
سال: 2019
ISSN: 1748-717X
DOI: 10.1186/s13014-019-1262-8